Florida has made limited progress in establishing a master business index to streamline business start-up requirements. Other states have developed web portals that make it easier for businesses to obtain needed start-up licenses, permits, and registrations and have reported benefits to both businesses and the state. If the Legislature chooses to implement a business one-stop portal in Florida, it should consider key success factors identified by other states, including establishing clear system objectives, a strong governance and accountability structure, mandatory agency participation, and provisions for stakeholder input.